People taking Antabuse should not drink alcohol or consume it within twelve hours of their dosage. In fact, it is recommended to separate the administration of these medicines from levothyroxine by 4 hours. You should also take Synthroid at least 4 hours before or after certain drugs that can affect how effective Synthroid is. In some cases, Antabuse can lead to severe liver damage, necessitating discontinuation of the medication. In some cases, your doctor may recommend other treatments or med...